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BMJ-British Medical Journal

Obesity in middle-aged women cuts chance of a long and healthy life by
almost 80 percent


The more weight women gain from the age of 18 until middle age, the less
likely they are to enjoy a long and healthy life, according to new
research published on bmj.com today.

     Compared with lean women, the results show that being obese in middle
age reduces those odds by 79%
, underscoring the importance of
maintaining a healthy weight from early adulthood, say the authors.

Healthy survival referred to participants who survived to age 70 years
or older, were free of major chronic diseases, and had good cognitive,
physical and mental health. Usual survival referred to participants who
survived to age 70 years or older but did not meet these criteria.

     The worst odds of healthy survival were found among women who were
overweight at 18 and gained 10kg or more by middle age.

But even among women who were lean at 18, relative to those who kept a
stable weight, women who gained more than 10kg by middle age were 59%
less likely to achieve healthy survival.

     "Given that more and more Americans are surviving to older ages and, at
the same time, gaining weight, our results may be particularly important
with respect to clinical or public health policies and deserve further
investigation and confirmation in additional studies," they conclude.


NEUROLOGY 2008;71:639-643
© 2008
American Academy of Neurology

Denture cream  (and zinc toxicity)

An unusual source of excess zinc, leading to hypocupremia and neurologic disease

S. P. Nations, MD, et al
 
Chronic, excess zinc intake can result in copper deficiency and profound neurologic disease
. However, when hyperzincemia is identified, the source often remains elusive. We identified four patients, one previously reported, with various neurologic abnormalities in the setting of hypocupremia and hyperzincemia. Each of these patients wore dentures and used very large amounts of denture cream chronically.

Objective: To determine zinc concentration in the denture creams used by the patients as a possible source of excess zinc ingestion.

 

Results: Zinc concentrations ranging from about 17,000 to 34,000 µg/g were identified in Fixodent and Poli-Grip denture creams. Serum zinc levels improved in three patients following cessation of denture cream use. Copper supplementation resulted in mild neurologic improvement in two patients who stopped using denture cream. No alternative source of excess zinc ingestion or explanation for hypocupremia was identified.


Conclusion:
Denture cream contains zinc, and chronic excessive use may result in hypocupremia and serious neurologic disease.


Abbreviations:
Hct = hematocrit; MRC = Medical Research Council; NCS = nerve conduction study; WBC = white blood cell.

 







Red wine may be good for your heart, but it looks like
white wine is bad for your teeth. It's not the alcohol in the wine that wears away tooth enamel, but the acidity of the wine. Sweet as it may be, Riesling rates lowest on the pH scale, meaning it's most acidic, and therefore worst for your teeth. However, pairing white wine with cheese may help counter the destructive effect. The calcium in the cheese helps neutralize your saliva and halts the acid's assault on your dental enamel. If you're looking to sip tooth-friendly wine, opt for a Rioja or Pinot Noir. But do note, red wine can stain teeth.

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